Van de Ven Brace Ends Everton's Run at Brand New Home Ground
Micky van de Ven emerged as the initial backline player to score twice in a English top-flight game for Spurs since Jan Vertonghen in spring 2013.
At a glance
The Spurs defender heads into the net twice in opening period
Everton's Jake O'Brien has equalizer ruled after VAR review
Pape Matar Sarr scores final goal in 89th minute
This loss is Everton's first at Hill Dickinson Stadium
Micky van de Ven found the net on two occasions as Spurs extended their winning streak on the road in the top division and delivered Everton their first defeat at Hill Dickinson Stadium.
The Toffees were unbeaten in their last five matches at their recently opened stadium at Bramley-Moore Dock, having departed Goodison Park behind after more than a century at the end of last season.
But Spurs captain Van de Ven pounced on two occasions from set-pieces in the opening 45 minutes to put their impressive record at jeopardy, and they were unable to turn it around before the midfielder - assisted by ex-Everton forward Richarlison - nodded in a final goal to put the game to bed.
Jake O'Brien believed he had equalized the scores a short while after Van de Ven's first goal, directing a powerful header past Guglielmo Vicario from an Everton corner.
The Portuguese striker, meanwhile, failed to convert a number of opportunities, while the Italian goalkeeper made a succession of fine saves to guarantee Tottenham went five matches on the road unbeaten in the English top flight.
But the video assistant referee intervened, instructing the match official to check the goal on the screen and the referee decided that Jack Grealish and the attacker were in offside positions and had interfered with the Tottenham goalkeeper.
The win moves Thomas Frank's side up to third in the Premier League, a handful of points off north London rivals and table-toppers Arsenal.
Everton stay in 14th position and are half a dozen points ahead of the relegation zone.
Spurs breakdown: Van de Ven fulfils role at both ends of the field
After a uninspiring weekday performance in the Champions League against Monaco, where they mustered a only two shots on target, Frank opted for the French striker up front instead of former Toffees player the Brazilian.
The new arrival was failed to influence the game before being replaced for Richarlison after 60 minutes on the field, but it turns out he proved unnecessary in the end.
Defender Van de Ven transformed into an offensive threat to be reckoned with.
Spurs' opening strike came from a well-worked corner routine, with Rodrigo Bentancur heading the ball back across the six-yard box for an free the defender to score.
And Ven de Ven - stepping up as skipper in the Argentine's unavailability - notched his second in first-half stoppage time as he outjumped the England keeper to nod in.
The Dutchman was just as impressive in defensive duties, combining effectively with Kevin Danso as the pair dealt excellently with the 34 crosses sent their way by the opposition.
Everton analysis: Toffees lacking striker's instinct
Everton's recent stadium had been a happy hunting ground, but it appears the novelty may have worn off somewhat and supporters headed to the gates after Sarr's final goal for Tottenham.
The break in Everton's winning streak at home won't be a major worry for the manager, but their striker situation will be.
The forward and the other striker - the Everton's two established strikers - had scored only a single goal between them before the weekend's outing.
And they were unable to add to that poor record on a damp and dreary evening on in Liverpool.
Beto's form was summed up when he opted to overhead kick a golden opportunity from close range, despite having space and time to readjust for a simpler attempt that would have tested the keeper.
Barry, too, failed to influence the game after replacing the starter in the 65th minute.
It wasn't for a lack of chance. Most of Everton's attacks came through Grealish and Ndiaye, who tirelessly whipped dangerous crosses into the Tottenham penalty area.
Upcoming fixtures for both teams?
Everton: Moyes' men travel to the Stadium of Light in the Premier League on early November at 20:00 GMT.
Tottenham: Spurs go to St James' Park on late October for their next round League Cup match against Newcastle.